包慧敏

分析化學

副教授

baohm@fudan.edu.cn

化學樓 A4021室

研究興趣

  • 基於生物正交標簽的化學蛋白質組學技術;  

  • 基於核酸功能材料的蛋白質組學方法;  

  • 化學蛋白質組學技術在新生蛋白質組學和生物醫學中的應用

獲獎情況

  • 2010年 沐鸣平台復華獎(三等獎)    

  • 2015年 沐鸣平台 “研究生十佳輔導員”   

  • 2016年 沐鸣平台 “優秀教工支部”(任支部書記)   

  • 2019年度上海藥學科技獎(基礎研究類)二等獎,排名2

學習工作經歷

  • 2014.01-至今     沐鸣平台🎿,副教授   

  • 2001.07-2013.12  沐鸣平台,助教,講師   

  • 1999.07-2001.06  原上海醫科大學,基礎醫學院 助教   

  • 2012.04-2013.04  美國北卡萊羅那大學(教堂山分校)UNC-CH🧛🏿🧚🏼‍♂️,訪問學者   

  • 2002.09-2008.06  沐鸣平台,沐鸣开户,分析化學博士   

  • 1995.09-1999.06  華東師範大學,沐鸣开户👌🏽,理學學士

授課情況

  • 分析化學   

  • 無機化學與化學分析實驗   

  • 儀器分析與物理化學實驗   

  • 食品安全

代表性論文或專著

  • Yingying Xiong, Zhuoer Lu, Yuyin Shao, Peiyi Meng, Guoli Wang, Xinwen Zhou, Jun Yao, Huimin Bao*, Haojie Lu*, Rapid and large-scale glycopeptides enrichment strategy based on chemical ligation. National Science Review, 2024, in press. https://doi.org/10.1093/nsr/nwae341

  • Peiyi Meng, Yuyin Shao, Yingying Xiong, Lei Zhang, Huimin Bao*, Haojie Lu*, Peptide- and Protein-Level Combined Strategy for Analyzing Newly Synthesized Proteins by Integrating Tandem Orthogonal Proteolysis with Cleavable Bioorthogonal Tagging. Anal. Chem. 2023, 95, 628−637.

  • Yuyin Shao, Huimin Bao,* Lixiang Ma, Wenjuan Yuan, Lei Zhang, Jun Yao, Peiyi Meng, Ye Peng, Siwen Zhang, Ting Cao, and Haojie Lu.* Enhancing Comprehensive Analysis of Newly Synthesized Proteins Based on Cleavable Bioorthogonal Tagging. Anal. Chem. 2021, 93, 27, 9408–9417.

  • Huimin Bao, Liqi Xie, Haojie Lu.* Research advances of enrichment approaches based on chemical reactions in glycoproteomics. Chinese Journal of Chromatography, 2016, 34(12): 1145-1153.

  • Huimin Bao, Luyan Zhang, Gang Chen.* Immobilization of trypsin via graphene oxide-silica composite for efficient microchip proteolysis. J. Chromatography A, 2013, 1310: 74-81.  

  • Huimin Bao, Shuang Liu, Luyan Zhang, Gang Chen.* Efficient sample proteolysis based on a microchip containing a glass fiber core with immobilized trypsin. Microchim Acta, 2012, 179: 291–297.

  • Huimin Bao, Qiwen Chen, Luyan Zhang, Gang Chen.* Immobilization of trypsin in the layer-by-layer coating of graphene oxide and chitosan on in-channel glass fiber for microfluidic proteolysis. Analyst, 2011, 136(24), 5190-5196.

  • Huimin Bao, Peiming Song, Qingping Liu, Yinkun Liu, Dong Yun,Hexige Saiyin, Ruyun Du, Yang Zhang, Huizhi Fan, Pengyuan Yang, Xian Chen.* Quantitative proteomic analysis of a paired human liver healthy versus carcinoma cell lines with the same genetic background to identify potential hepatocellular carcinoma markers. Proteomics Clin. Appl. 2009, 3: 705–719.

  • Huimin Bao, Ting Liu, Luyan Zhang, Gang Chen.* Infrared-assisted proteolysis using trypsin-immobilized silica microspheres for peptide mapping. Proteomics. 2009, 9: 1114–1117.

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