師資隊伍
萬力
有機化學
青年副研究員
li_wan@fudan.edu.cn
沐鸣平台手性分子催化與合成工程中心 上海市手性藥物工業不對稱催化工程研究
研究興趣
流動化學🤍⁉️，微反應器
天然產物與藥物的全合成
碳氫鍵功能化
學習工作經歷
2022.01-至今 沐鸣开户🙎🏼，青年副研究員
2021.09-2021.12 華東理工大學🕘，化工學院，副教授
2017.10-2021.08 華東理工大學，化工學院🤕，講師
2014.07-2017.09 南京工業大學🌨💆，生工學院🐥，講師
2012.09-2013.09 美國斯克利普斯研究所，沐鸣开户有機化學專業聯合培養，導師🕺🏽：Jin-Quan Yu教授
2009.09-2014.06 南京理工大學，化工學院📔，博士，導師🈳：蔡春教授
2005.09-2009.06 南京理工大學🏝，化工學院，學士
代表性論文或專著
Q. Li, M. J. Liu, Y. J. Zhang, L. Wan,* F. E. Chen.* Scalable and integrated four-step continuous-flow synthesis of ibuprofen using a zinc-catalyzed 1,2-aryl migration strategy. ACS Sustainable Chem. Eng.2024, 12, 8512-8520.
S. Q. Huang, R. Q. Hao, Q. Li, L. Wan,* F. E. Chen.* Selective C–H functionalizations of arenes catalyzed by poly NHC–Pd in flow. React. Chem. Eng.2024, 9, 1641-1645.
Z. N. Li, S. Q. Huang, Y. Tao, M. F. Jiang, D. Cheng, L. Wan,* F. E. Chen.* An integrated five-step continuous flow synthesis of 2-(1-cyclohexenyl)ethylamine: a key intermediate for morphinans. React. Chem. Eng.2023, 8, 1882-1887.
L. Wan, M. F. Jiang, D. Cheng, M. J. Liu, F. E. Chen. Continuous flow technology-a tool for safer oxidation chemistry. React. Chem. Eng.2022, 7, 490-550.
L. Zhang, X. F. Bo, H. L. Yao, M. M. Mao, L. Wan,* Z. Xin*. Zinc-catalyzed alkylation of aromatic amines in continuous flow. Org. Process Res. Dev. 2020, 24, 2078-2084.
K. Qiao, D. Zhang, K. Zhang, X. Yuan, M. W. Zheng, T. F. Guo, Z. Fang, L. Wan*, K. Guo*. Iron(II)-catalyzed C-2 cyanomethylation of indoles and pyrroles via direct oxidative crossdehydrogenative coupling with acetonitrile derivatives. Org. Chem. Front.2018, 5, 1129-1134.
L. Wan, K. Qiao, X. Yuan, M. W. Zheng, B. B. Fan, Z. C. Di, D. Zhang, Z. Fang, K. Guo*. Nickel-catalyzed regioselective C-H bond mono- and bis-nitration of aryl oxazolines with TBN as nitro source. Adv. Syn. Cat.2017, 359, 2596-2604.
L. Wan, X. N. Sun, S. J. Shi, J. W. Zhang, X. Li, Z. J. Li, K. Guo*. An efficient synthesis of N-substituted phthalimides using SiO2-tpy-Nb as heterogeneous and reusable catalyst. Catal. Commun.2017, 88, 30-34.
L. Wan, W. T. Zhu, K. Qiao, X. N. Sun, Z. Fang, K. Guo*. C3 Alkylation of indoles catalyzed by carbocations under continuous-flow conditions. Asian J. Org. Chem.2016, 5, 920-926.
G. Li, L. Wan, G. F. Zhang, D. Leow, J. Spangler, J.-Q. Yu. Pd(II)-Catalyzed C−H functionalizations directed by distal weakly coordinating functional groups. J. Am. Chem. Soc.2015, 137, 4391-4397.
L. Wan, N. Dastbaravardeh, G. Li, J.-Q. Yu. Cross-coupling of remote meta-C–H bonds directed by an U-shaped template. J. Am. Chem. Soc.2013, 135, 18056-18059.
G. Li, D. Leow, L. Wan, J.-Q. Yu. Ether-directed ortho-C–H olefination with a palladium(II)/monoproctected amino acid catalyst. Angew. Chem., Int. Ed. 2013, 52, 1245-1247.
